Ctgf lncrna
WebApr 11, 2024 · During chronic hepatitis B virus (HBV) infection, hepatic fibrosis is a serious pathological condition caused by virus-induced liver damage. The activation of hepatic stellate cells (HSCs) is a central event in the occurrence and progression of liver fibrosis. Although accumulating evidence has shown that HBV directly stimulates HSC activation, … WebApr 23, 2024 · LncRNA PFAL was found to have profibrotic activity, which manifested itself upon the inhibition of miR-18a. ... (TGF-β1) and connective tissue growth factor (CTGF) …
Ctgf lncrna
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WebE. Expression analysis of LITATS1, PAI-1, CTGF, and SMAD7 in MCF10A-M2 cells upon CRISPRa-mediated LITATS1 overexpression. Representative results from a minimum of three independent experiments are shown. ... TGF-β signaling can induce the expression of multiple lncRNAs, e.g., lncRNA-ATB and lncRNA-HIT, which function as effectors of … WebOct 7, 2024 · The results showed that lncRNA H19 can affect the downstream molecular CTGF in KGN cells, and abnormally expressed CTGF can participate in the …
WebFeb 12, 2024 · 沈阳医学院学报 2024年5期. 沈阳医学院学报的其它文章 lncRNA靶向miRNA调控Wnt信号通路在结直肠癌中的研究进展 miRNA与宫颈癌的关系 WebDec 12, 2024 · During the proliferative phase of diabetic wound healing, lncRNA H19 recruits the transcription factor SRF to the CTGF promoter region, activating CTGF and its downstream MAPK signaling pathway to accelerate fibroblast proliferation and wound healing. These findings elaborate lncRNA H19 as a regulator in the regenerative phase …
WebJun 21, 2024 · A lncRNA known as lncRNA megacluster ( lnc-MGC) was found to play a key role in the pathogenesis of early DN ( 72 ). Lnc-MGC is a host gene for miR-379 cluster, i. e., harbors miRNAs in its exonic and intronic sequences and these non-coding RNAs are present within one of the largest miRNA clusters in the genome. WebApr 3, 2024 · One of the key mechanisms of cardiac diseases has recently been identified as long non-coding RNA (lncRNA) dysregulation. Through in vitro and in vivo studies, …
WebCTGF, also known as CCN2 or connective tissue growth factor, is a matricellular protein of the CCN family of extracellular matrix-associated heparin-binding proteins (see also CCN …
WebApr 23, 2024 · lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a. ... In the present study, we identified that lncRNA NONMMUT021928, … flug glasgow hamburgWebJun 8, 2024 · BackgroundChronic liver fibrosis is an inevitable stage for the development of patients with chronic hepatitis B (CHB). However, anti-fibrotic therapies have been … flughafen academy loginWebApr 23, 2024 · lncRNA PFAL promotes lung fibrosis through CTGF by competitively binding miR-18a. ... In the present study, we identified that lncRNA NONMMUT021928, designated as pulmonary fibrosis-associated lncRNA (PFAL), was up-regulated in the lungs of mice with experimental lung fibrosis, and in TGF-β1-induced fibrotic lung fibroblasts. Further … greene lyon group incWebMay 13, 2024 · lncRNA MIAT increases cell viability, migration, EMT and ECM production in age‑related cataracts by regulating the miR‑181a/CTGF/ERK signaling pathway May 2024 Experimental and Therapeutic ... flug grand canyon las vegasWebJan 8, 2024 · The TGFβ–ALK5 signaling axis can directly mediate inhibition of endothelial cell proliferation and migration (Fig. 5b). 160,161 Indirectly, the expression of some key angiogenic factors, such ... flughaefen londonWebDepleting MUF resulted in ~50% downregulation of Snail1, ~40% downregulation of vimentin, ~60% downregulation of CTGF, and ~30% downregulation of c-Myc in T98G cells and U87-MG cells (Figure 4B). Several other TGF-β-regulated genes did not show any change in expression with MUF knockdown . Since lncRNA-MUF depletion inhibits … flughafen academyWebApr 3, 2024 · Cui, Yue and Shi, Bozhong and Zhou, Zijie and Chen, Bo and Zhang, Xiaoyang and Li, Cong and Luo, Kai and Zhu, Zhongqun and Zheng, Jinghao and He, Xiaomin, LncRNA CFRL Aggravates Cardiac Fibrosis by Modulating Both miR-3113-5p/CTGF and miR-3473d/FN1 Axis. greenely pris