Estrogen-related receptor γ

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August undefined, 2024

Web核受体，又称为核内受体（英語： Nuclear receptor ）是细胞内一类转录因子的统称。核受体超家族的成员在细胞生长、发育、分化与新陈代谢均起到了重要的作用。由于核受体都位于细胞内部，因此它们的激素均为溶脂性，这样才能穿越由脂肪构成的细胞膜。对核受体的研究始于20世纪70年代，70年代 ... WebApr 12, 2024 · This is coherent with the previous studies, which reported that the anti-cancer properties of tocotrienols, including TRF, α-, γ- and/or δ-tocotrienol, were not dependent on estrogen receptor status [59,60]. Further study is required to confirm the role of HMG CoA reductase and estrogen receptor signaling in tocotrienol-mediated ERS and cell ...

Estrogen-Related Receptor - an overview ScienceDirect Topics

WebFeb 18, 2009 · While the activities of estrogen receptors are stimulated by agonists, ERRs are constitutively active receptors that display strong transcriptional activities particularly in conjunction with their coactivator peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) [15].We then asked if kaempferol would affect the activities of ERRα and … WebEstrogen-related receptor γ (EERγ)–corepessor peptide silencing mediator for retinoid or thyroid-hormone receptors (SMRT) interaction. Partial agonist-bound EERγ exhibits … dr westly mori

Estrogen‑related receptor γ promotes the migration and metastasis …

WebJul 1, 2024 · Here, we aim to elucidate the function of estrogen-related receptor γ (ERRγ) in pancreatic acinar cell mitochondrial homeostasis and energy production. Methods Two … WebJan 1, 2008 · BackgroundVarious lines of evidence have shown that bisphenol A [BPA; HO-C6H4-C(CH3)2-C6H4-OH] acts as an endocrine disruptor when present in very low doses. We have recently demonstrated that BPA binds strongly to human estrogen-related receptor-γ (ERR-γ ) in a binding assay using [3H]4-hydroxytamoxifen ([3H]4-OHT). We … WebEstrogen receptors (ERs) are a group of proteins found inside cells.They are receptors that are activated by the hormone estrogen (17β-estradiol). Two classes of ER exist: … dr westmacott

Key regulator of cellular metabolism, estrogen-related receptor …

WebMay 11, 2024 · Triclosan (TCS) and triclocarban (TCC) are two widely used antimicrobial agents that have been reported to be estrogenic disruptors. Previous researches have shown that TCC and TCS exhibit weak or no agonistic activity on classical estrogen receptors. We demonstrate first in the present study that TCS and TCC disrupt the … WebApr 4, 2024 · ESRRG. estrogen related receptor gamma. Gene ID: 2104, updated on 8-Dec-2024. Gene type: protein coding. Also known as: ERR3; ERRg; NR3B3; … comfort conditioner asdaWebThe C-terminal fragment of the β-amyloid precursor protein produced after cleavage by γ-secretase, ... of β-Amyloid Precursor Protein Signaling into the Nucleus by Estrogens Mediated through Complex Formation between the Estrogen Receptor and Fe65. ... Related research . comfort concepts bettendorf

"WebEstrogen-related receptor (ERR)γ is an orphan nuclear hormone receptor that belongs to the ERR subfamily of transcription factors. No endogenous ligand has been identified to date. ERRγ possesses ligand-independent transcriptional activity that is regulated by co-regulator interactions, and post-translational modifications (PTMs). ... " - Estrogen-related receptor γ

Estrogen-related receptor γ

Expression of estrogen-related receptors in ovarian cancer

WebERRα as a master metabolism regulator was well known to have an important role in maintaining cancer phenotypes by altering cellular bioenergetics 26, 27 Investigating an estrogen signaling-independent function for the ERRα in tumor is arousing increasing interest. In conclusion, the PGC-1α/ERRα axis, as the key point of energy metabolism ... WebFOXP2（Forkhead box protein P2）基因，即叉头框P2基因，是一个与言语功能的发育有关的基因。在人类，FOXP2基因位于7号染色体上。 FOXP2基因在许多其它具有复杂发声、及发声学习能力的动物，例如鸣禽中，也有发现。该基因的异常在人类导致特定的先天性言语 …

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WebDec 17, 2024 · The human estrogen-related receptor γ (ERRγ) is an orphan nuclear receptor. The ERRγ behaves as a constitutive activator of transcription and plays a key role in controlling mitochondrial energy production and energy metabolism. Bisphenol A (BPA) is used mainly in producing polycarbonate plastics and epoxy resins, but it is known as an ... Web1 hour ago · Go-6893 reduces the LHb PKC-γ, βCaMKII-AMPA receptor-related molecules’ proteins levels in Post-EtOH ... Evidence for estrogen receptor in cell nuclei and axon …

WebPGC-1α is a transcriptional coactivator that regulates the genes involved in energy metabolism. It is the master regulator of mitochondrial biogenesis. [6] [7] [8] This protein interacts with the nuclear receptor PPAR-γ, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and ... WebMar 23, 2024 · Here, we identify a molecular mechanism showing that orphan nuclear receptor estrogen-related receptor γ (ERRγ) regulates LOX gene expression in the …

Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a nuclear receptor that in humans is encoded by the ESRRG (EStrogen Related Receptor Gamma) gene. It behaves as a constitutive activator of transcription. This protein is a member of … See more There is evidence that bisphenol A functions as a xenoestrogen by binding strongly to ERR-γ. BPA as well as its nitrated and chlorinated metabolites seems to binds strongly to ERR-γ (dissociation constant = … See more • Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791 See more • "Master protein found to enhance both muscles and the brain". KurzweilAI. April 7, 2015. See more WebEstrogen-related receptor γ agonist; promotes maturation of hiPSC-derived cardiomyocytes: Estrogen and Related Receptor Inverse Agonists; Cat. No. Product Name / Activity; ... Three estrogen-related receptors (ERRs) - ERRα, ERRβ and ERRγ - have also been identified. Classified as 'orphan' nuclear receptors, they do not bind …

WebDec 15, 2014 · Estrogen-related receptor α and estrogen-related receptor γ associate with unfavorable and favorable biomarkers, respectively, in human breast cancer. …

WebFeb 9, 2024 · Estrogen-related receptor γ (ERRγ) has been reported as the most likely major target NR of BPA [9, 10, 12]. Including other estrogen-related receptors ERRα and ERRβ, all of these NRs associated with the term ‘estrogen’ appear often to exist simultaneously in some of the same cells [ 18 – 22 ]. comfort concealment bandWebFeb 1, 2024 · Introduction. Breast cancer is the leading cause of cancer-related deaths in women worldwide (Sung et al., 2024).Most breast cancers express specific hormone receptors (HRs) for estrogen (estrogen receptor α, ERα) and progesterone (progesterone receptor, PR), and some cancers exhibit human epidermal growth factor receptor 2 … comfort concepts austin arWebRAR相关孤儿受体（英語： RAR-related orphan receptor ，RORs）是核受体的一个家族，是细胞内转录因子的一员。有三个ROR家族成员：ROR-α、-β和-γ分别由基因RORA、RORB、RORC编码。 RORs的不寻常之处在于它们是以单体形式结合到激素反应元件（英语： hormone response element ）上的，而其它大部分核受体都是 ... comfort concepts cabot arWebApr 21, 2024 · ERRγ is an orphan nuclear receptor and a member of the ERR subfamily, including ERRα and ERRβ. Transcriptional activity of ERRs is enhanced by PGC-1 family coactivators and together orchestrate … comfort concepts incWebOct 4, 2024 · This locus contains the estrogen related receptor γ (Esrγ), expressed in T cells, which encodes for an orphan nuclear receptor that controls mitochondrial function and oxidative metabolism. B6Sle1c2 CD4 T cells expressed reduced levels of Esrγ, which correlated inversely with CD4 activation compared to B6 CD4 T cells. dr westman eating planWebJul 1, 2011 · Here, we aim to elucidate the function of estrogen-related receptor γ (ERRγ) in pancreatic acinar cell mitochondrial homeostasis and energy production. Two models of ERRγ inhibition, GSK5182-treated wild-type mice and ERRγ conditional knock-out (cKO) mice, were established to investigate ERRγ function in the exocrine pancreas. To identify ... comfort concepts chill mattress reviewsWebMay 11, 2024 · Estrogen-Related Receptor γ than Triclosan at Human Exposure. Levels: A Novel Estrogenic Disruption Mechanism. Lin-Ying Cao, * Yun-Hao Xu, Sen He, Xiao-Min Ren, Yuan Yang, Shuang Luo, Xian-De Xie ... comfort conditioner 78 washes