Irf8 genecards

WebDetroit is a city located in Wayne County Michigan.It is also the county seat of Wayne County.With a 2024 population of 621,193, it is the largest city in Michigan and the 27th … WebIRF8 is highly expressed in myeloid cells and was originally identified in as a critical lineage-specific transcription factor for myeloid cell differentiation, [7] recent studies, however, …

IRF8 Impacts Self‐Renewal of Hematopoietic Stem Cells by Regulating …

WebProtein Interferon regulatory factor 8 Gene Irf8 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 424 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function WebIRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including the type I interferon genes. In particular, IRF7 regulates many interferon-alpha genes. [5] cseari https://mechanicalnj.net

IRF8 Gene - GeneCards IRF8 Protein IRF8 Antibody

WebIRF8: Interferon Regulatory Factor 8: Protein Coding: Q02556: 52: GC16P085898: 104.12: 2: FOXF1: Forkhead Box F1: Protein Coding: Q12946: 48: GC16P086510: 13.39: 3: … WebMar 10, 2011 · IRF8 is an essential transcriptional regulator of IFN-β expression in monocytes We hypothesized that IRF8, a transcription factor found only in lymphoid and myeloid cells such as macrophages, 24, 32 might be involved. WebMar 25, 2024 · IRF8 has also been found to be expressed and functional in non-hematopoietic cells such as epithelial cells [ 7, 8 ]. Studies of IRF8 mRNA levels in normal human colon and colorectal carcinoma (CRC) revealed that IRF8 is downregulated in tumor tissues as compared to non-malignant counterpart tissues. cse arousiney

IFN regulatory factor 8 is a key constitutive determinant of the ...

Category:Frontiers Mutation in Irf8 Gene (Irf8R294C) Impairs Type I IFN ...

Tags:Irf8 genecards

Irf8 genecards

The BXH2 mutation in IRF8 differentially impairs dendritic cell subset …

WebThe strengths of this test include: CAP accredited laboratory; CLIA-certified personnel performing clinical testing in a CLIA-certified laboratory WebRoseville, MI. $25. AM/FM radio vintage/antique 50’s . West Bloomfield, MI. $25. Vintage 1994 Joe’s Place 4 Plastics Cups & 1991 Hard Pack 5 Different Camel Characters Lighters …

Irf8 genecards

Did you know?

WebMar 21, 2024 · IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma. Global assessment of IRF8 as a novel cancer biomarker. Predicting the … WebIFN regulatory factor (IRF) 8 is a transcription factor that has a key role in the cellular response to IFN-γ and is pivotal in myeloid cell differentiation. Whether IRF8 plays a role in the development and function of microglia, the tissue-resident myeloid cells of …

WebInterferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. [5] [6] [7] IRF8 is … WebInterferon regulatory factor 8 (Irf8), also known as interferon consensus sequence-binding protein, is a component of the Irf transcription factor family. Irf8 is differentially expressed …

WebMar 21, 2024 · IRF8 (Interferon Regulatory Factor 8) is a Protein Coding gene. Diseases associated with IRF8 include Immunodeficiency 32A and Immunodeficiency 32B. Among … WebOct 4, 2024 · IRF8, or ICSBP, is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. The family also includes IRF1 ( 147575 ), IRF2 ( 147576 ), and ISGF3 (see …

WebSep 20, 2016 · Interferon regulatory factor-8 (IRF8) has been proposed to be essential for development of monocytes, plasmacytoid dendritic cells (pDCs) and type 1 conventional …

Web(Click on the icon in the table below to see search hit context) dyson pet hair removal attachmentWebFeb 15, 2008 · IRF8 binds to certain DNA motifs such as ISRE and Ets/IRF composite elements by interacting with partner proteins that include IRF members and Ets family proteins. 12, 15 Although IRF8 can regulate gene expression through other mechanisms, the interaction with partners is thought to be a critical requirement for macrophage … cse armor proteinesWebJan 14, 2024 · MalaCards Gene Search: IRF8 Diseases sorted by gene-association score: immunodeficiency 32a, mycobacteriosis, autosomal dominant* (1650), immunodeficiency … dyson pet hair turbine toolWebAug 24, 2024 · IRF8 was originally identified as an essentialfactor for myeloid cell lineage commitment and differentiation. Deletion of Irf8 leads to massive accumulation of CD11b + Gr1 + immature myeloid cells (IMCs), particularly the CD11b + Ly6C hi/+ Ly6G - polymorphonuclear myeloid-derived suppressor cell-like cells (PMN-MDSCs). csearll game flareWebMar 29, 2024 · Detroit, city, seat of Wayne county, southeastern Michigan, U.S. It is located on the Detroit River (connecting Lakes Erie and St. Clair) opposite Windsor, Ontario, … dyson pet hair hoover attachmentWebSymbol Description Category UniProt ID GIFtS GC id Score; 301: PPARGC1A: PPARG Coactivator 1 Alpha: Protein Coding: Q9UBK2: 53: GC04M023755: 0.43: 302: PTPRO: Protein Tyrosine Phosphatase Receptor Type O dyson pet stick vacuum cleanerWebNov 17, 2024 · IRF8 R294C mice were crossed with C57BL/6 wild-type female for at least three generations to eliminate the vertical transmission of Murine Leukemia Virus (MuLV). Progenies were crossed to generate the mice carrying homozygous alleles for the mutation, and all the mice were used at the age of 8–12 weeks. csear ri