Ttc9a

WebAug 12, 2008 · TTC9A (1–100), which contains the first TPR domain, interacted with Tm5NM-1 to some extent but the interaction was weaker than TTC9A (1–115). Since the first TPR domain lies in residues 57–90, it is plausible that the first TPR domain is required for the interaction. WebSep 6, 2024 · It is plausible therefore that TTC9A negatively regulates ERalpha activity through interacting with co-chaperone proteins such as FKBP38 and FKBP51. TTC9A acts …

TTC9A deficiency induces estradiol-mediated changes in …

WebApr 1, 2024 · In brief, Ttc9a-/-and wildtype female mice were subjected to ovariectomy (OVX) as reported (Lim et al., 2016; Lin et al., 2001). After a 10-day recovery period, mice were administered a subcutaneous injection of either 10 μg/kg 17-β-estradiol benzoate . Effects of Ttc9a-/-and estradiol modulation on tail suspension immobility WebNov 21, 2016 · Tetratricopeptide repeat domain 9A (TTC9A) expression is abundantly expressed in the brain. Previous studies in TTC9A knockout (TTC9A−/−) mice have … hill street blues conrad https://mechanicalnj.net

Gene Regulation in Breast Cancer - School of Biological Sciences

WebTTC9A deficient mammary gland showed significant increase in mammary ductal elongation and branching on estrogen and progesterone treatment, demonstrating … WebTTC9A to be 222 aa. Using mouse polyclonal antibody generated against TTC9A protein, TTC9A was shown to be ubiquitously expressed in human tissues. In breast cancer cells, TTC9A was predominantly concentrated to the endoplasmic reticulum and was regulated by a number of factors, such as growth factors, serum factors and steroid hormones [2]. WebTo understand the effects of TTC9A and estradiol modulation on neuroplasticity functions, we performed a behavioral analysis of tail suspension immobility and neuroplasticity-related gene expression study of brain samples collected in a previous study involving ovariectomized (OVX) Ttc9a-/- mice with estradiol or vehicle treatment. hill street blues let\\u0027s be careful out there

Anti-TTC9 antibody produced in rabbit - Sigma-Aldrich

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Ttc9a

Tetratricopeptide repeat domain 9A is an interacting protein for ...

Webstudies in TTC9A knockout (TTC9A−/−) mice have indicated that TTC9A negatively regulates the action of estrogen. In this study we investigated the role of TTC9A on … WebWe'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2024 ...

Ttc9a

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WebAnti-TTC9 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution; Synonyms: Anti … WebTTC9A through estradiol action in emotional control. Although we know that Ttc9a-/- induces anxiety-like behavior through the effect of estradiol on serotonergic system 9, the …

WebSep 14, 2012 · 1. Introduction. Tetratricopeptide repeat domain 9A (TTC9A) is a member of TTC9 family proteins that also include TTC9B and TTC9C. Human TTC9A gene was first identified by sequence analysis of a cDNA clone from a brain cDNA library .It was confirmed to code for a 222 amino acid TTC9A protein in human using mouse polyclonal antibody … WebLi Quan, Wing Shan Yu, Smeeta Shrestha, Yu Zuan Or, Thomas Lufkin, Ying-Shing Chan, Valerie CL Lin and Lee Wei Lim (2024) TTC9A deficiency induces estradiol-mediated …

WebAbstract. Tetratricopeptide repeat domain 9A (TTC9A) is a target gene of estrogen and progesterone.It is over-expressed in breast cancer. However, little is known about the physiological function of TTC9A.The objectives of this study were to establish a Ttc9a knockout mouse model and to study the consequence of Ttc9a gene inactivation. The … WebThe involvement of tetratricopeptide repeat domain 9A (TTC9A) deficiency in anxiety-like responses and behavioral despair through estradiol action on the serotonergic system has been reported. Emerging evidence suggests that estradiol is a potent modulator of neuroplasticity. As estradiol and neurop …

WebSep 14, 2012 · TTC9A was induced by mitogens, estrogen and growth factors in breast cancer cells MCF-7 [2]. TTC9A expression is also significantly higher in breast cancer tissues than the adjacent normal tissues [17]. These indicate that TTC9A expression is positively associated with cell proliferation and the presence of growth-stimulating signals.

WebDC Field Value Language; dc.contributor.author: Shrestha, Smeeta: en: dc.contributor.author: Sun, Yang: en: dc.contributor.author: Lufkin, Thomas: en: dc.contributor ... smart build homesWebPrimePCR™ Template for Probe Assay: TTC9, Human Reaction: 200 x 20 µl reactions Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay. hill street blues buntzWebFeb 10, 2024 · This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our privacy notice and privacy notice and smart build hardwareWebApr 1, 2024 · Since Ttc9a is induced by estrogen in estrogen target tissues, these results suggest that Ttc9a is a negative regulator of estrogen function through a negative … smart build hexagonsmart build incWebTo understand the effects of TTC9A and estradiol modulation on neuroplasticity functions, we performed a behavioral analysis of tail suspension immobility and neuroplasticity … smart build northamptonWebMay 2009 - Sep 20123 years 5 months. Nanyang Technological University, Singapore. • Perform hands-on wet lab work to generate TTC9A mutant … smart build insight